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Peter Koopman Selected Research

SOXF Transcription Factors

11/2021A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
1/2017Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
1/2012Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.
8/2006Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development.

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Peter Koopman Research Topics

Disease

5Neoplasms (Cancer)
04/2016 - 08/2006
4Telangiectasis (Telangiectasia)
11/2021 - 02/2004
4Hypotrichosis
11/2021 - 02/2004
3Gonadal Dysgenesis (Gonadal Agenesis)
01/2022 - 09/2009
3Lymphedema (Milroy Disease)
11/2021 - 02/2004
3Neoplasm Metastasis (Metastasis)
02/2014 - 01/2012
2XX Disorders of Sex Development 46 (Female Pseudohermaphroditism)
01/2022 - 11/2016
246,XY Disorder of Sex Development (Male Pseudohermaphroditism)
12/2018 - 11/2016
2Breast Neoplasms (Breast Cancer)
01/2017 - 08/2006
2Melanoma (Melanoma, Malignant)
06/2012 - 08/2006
2Disorders of Sex Development (Intersexuality)
07/2011 - 12/2009
1Inborn Genetic Diseases (Disease, Hereditary)
11/2021
1Hypospadias
12/2018
1Seminoma
04/2016
1Endodermal Sinus Tumor (Endodermal Sinus Tumors)
04/2016
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
04/2016
1Embryonal Carcinoma
04/2016
1Acrocephalosyndactylia (Apert Syndrome)
12/2015
1Virilism (Virilization)
06/2015
1Carcinogenesis
05/2014
1Malnutrition (Nutritional Deficiencies)
02/2012
1Infertility (Sterility)
01/2012
1Epidermolysis Bullosa
01/2012
1ATR-X syndrome
06/2011
1Retinoblastoma (Glioblastoma, Retinal)
02/2010
1Frasier Syndrome
09/2009
1Hypoxia (Hypoxemia)
09/2005
1Inflammation (Inflammations)
02/2004
1Atherosclerosis
02/2004
1Blepharophimosis
07/2003

Drug/Important Bio-Agent (IBA)

4SOXF Transcription FactorsIBA
11/2021 - 08/2006
4Proteins (Proteins, Gene)FDA Link
04/2016 - 12/2009
4Transcription Factors (Transcription Factor)IBA
07/2011 - 12/2008
2Vitamin A (Retinol)FDA LinkGeneric
02/2012 - 01/2012
1NucleotidesIBA
01/2022
1Steroidogenic Factor 1IBA
12/2018
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
12/2018
1ElementsIBA
12/2018
1DNA (Deoxyribonucleic Acid)IBA
11/2016
1Amino AcidsFDA Link
12/2015
1SteroidsIBA
06/2015
1Hormones (Hormone)IBA
06/2015
1RNA-Binding Proteins (RNA-Binding Protein)IBA
05/2014
1Vascular Endothelial Growth Factor DIBA
02/2014
1Firefly LuciferasesIBA
06/2012
1Androgen Receptors (Androgen Receptor)IBA
06/2011
1Protein Isoforms (Isoforms)IBA
09/2009
1Bromodeoxyuridine (BrdU)IBA
08/2006
1AntibodiesIBA
08/2006
1RNA (Ribonucleic Acid)IBA
09/2005
1Aggrecans (Aggrecan)IBA
09/2005
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
02/2004
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
07/2003

Therapy/Procedure

2Therapeutics
01/2012 - 08/2006